This leads to the proposal of a novel self-supervised solution based on a masked loss function. We evaluate our method using both simulated and real data. On simulated data from a conventional video, we achieve 34.35 mean PSNR with extremely photon-sparse binary input (<0.06 photons per pixel per frame).

Neural Information Processing Systems http://nips.cc/

The red lines in the bottom plot indicate linear fits and the red axis labels show the rank correlation coefficients ρ and p values. The matrix is orthogonal, thus avoiding a singular design. As scGen returns corrected input data, we performed PCA on the output data, which were used for further evaluation (cf. Appendix Section A.1). Here, we used the same number of principle components (PCs) as used for Embedded cells are colored by dataset. In Figure 9, we present the results of the simulation experiments discussed in the main text.

We study online change point detection problems under the constraint of local differential privacy (LDP) where, in particular, the statistician does not have access to the raw data. As a concrete problem, we study a multivariate nonparametric regression problem. At each time point $t$, the raw data are assumed to be of the form $(X_t, Y_t)$, where $X_t$ is a $d$-dimensional feature vector and $Y_t$ is a response variable. Our primary aim is to detect changes in the regression function $m_t(x)=\mathbb{E}(Y_t |X_t=x)$ as soon as the change occurs. We provide algorithms which respect the LDP constraint, which control the false alarm probability, and which detect changes with a minimal (minimax rate-optimal) delay. To quantify the cost of privacy, we also present the optimal rate in the benchmark, non-private setting. These non-private results are also new to the literature and thus are interesting \emph{per se}. In addition, we study the univariate mean online change point detection problem, under privacy constraints. This serves as the blueprint of studying more complicated private change point detection problems.

The performance of machine learning models on tabular data is critically dependent on high-quality feature engineering. While Large Language Models (LLMs) have shown promise in automating feature extraction (AutoFE), existing methods are often limited by monolithic LLM architectures, simplistic quantitative feedback, and a failure to systematically integrate external domain knowledge. This paper introduces Rogue One, a novel, LLM-based multi-agent framework for knowledge-informed automatic feature extraction. Rogue One operationalizes a decentralized system of three specialized agents-Scientist, Extractor, and Tester-that collaborate iteratively to discover, generate, and validate predictive features. Crucially, the framework moves beyond primitive accuracy scores by introducing a rich, qualitative feedback mechanism and a "flooding-pruning" strategy, allowing it to dynamically balance feature exploration and exploitation. By actively incorporating external knowledge via an integrated retrieval-augmented (RAG) system, Rogue One generates features that are not only statistically powerful but also semantically meaningful and interpretable. We demonstrate that Rogue One significantly outperforms state-of-the-art methods on a comprehensive suite of 19 classification and 9 regression datasets. Furthermore, we show qualitatively that the system surfaces novel, testable hypotheses, such as identifying a new potential biomarker in the myocardial dataset, underscoring its utility as a tool for scientific discovery.